Design and analysis of non-inferiority trials / Mark D. Rothmann, Brian L. Wiens, Ivan S.F. Chan.
Material type:
TextSeries: Chapman & Hall/CRC biostatistics seriesPublication details: Boca Raton, Fla. : Chapman & Hall/CRC, 2011.Description: xvi, 438 p. ; 25 cmISBN: - 9781584888048
- RM301.27 .R68 2011
- Also available as an electronic resource.
| Item type | Current library | Call number | Status | Date due | Barcode | Item holds | |
|---|---|---|---|---|---|---|---|
| Books | ISI Library, Kolkata NBHM Collection | 615.580724 R846 (Browse shelf(Opens below)) | Available | 133206 |
Browsing ISI Library, Kolkata shelves, Shelving location: NBHM Collection Close shelf browser (Hides shelf browser)
| No cover image available | No cover image available | |||||||
| 614.4 M414 Fuzzy logic in action | 615.5072 F911 Fundamentals of clinical trials | 615.50724 C539 Adaptive and flexible clinical trials / | 615.580724 R846 Design and analysis of non-inferiority trials / | 615.70184 N864(87) Pharmacokinetics : mathematical and statistical approaches to metabolism and distribution of chemicals and drugs : proceedings | 616.07570151 G316 Mathematical problems of tomography | 620.0011 R881 System dynamics : an introduction |
"A Chapman & Hall book."
Includes bibliographical references and index.
1. What is a non-inferiority trial? -- 2. Non-inferiority trial considerations -- 3. Strength of evidence and reproducibility -- 4. Evaluating the active control effect -- 5. Across-trials analysis methods -- 6. Three-arm non-inferiority trials -- 7. Multiple comparisons -- 8. Missing data and analysis sets -- 9. Safety studies -- 10. Additional topics -- 11. Inference on proportions -- 12. Inferences on means and medians -- 13. Inference on time-to-event endpoints.
"The increased use of non-inferiority analysis has been accompanied by a proliferation of research on the design and analysis of non-inferiority studies. Design and Analysis of Non-Inferiority Trials brings together this body of research and confronts the issues involved in the design of a non-inferiority trial. Using examples from real clinical trials, the book discusses general and regulatory issues and illustrates how they affect analysis. Each chapter begins with a non-technical introduction, so the subject is easily understood by those without prior knowledge of non-inferiority clinical trials. The book also provides detailed mathematical approaches along with their mathematical properties"--Provided by publisher.
Also available as an electronic resource.
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