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Randomized phase II cancer clinical trials / Sin-Ho Jung.

By: Material type: TextTextSeries: Chapman & Hall/CRC biostatistics seriesPublication details: Boca Raton, Fla. : Taylor & Francis Group, c2013.Description: 229 p. : ill. ; [ca. 23-29] cmISBN:
  • 9781439871850
Subject(s): Available additional physical forms:
  • Also available as an electronic resource.
Contents:
1. Introduction -- 2. Single-arm phase II trial designs -- 3. Inference on the binomial probability in single-arm multistage clinical trials -- 4. Single-arm phase II clinical trials with time-to-event endpoints -- 5. Single-arm phase II trials with heterogeneous patient populations : binary and survival outcomes -- 6. Randomized phase II trials for selection : no prospective control arms -- 7. Randomized phase II cancer clinical trials with a prospective control on binary endpoints (I) : two-sample binomial test -- 8. Randomized phase II cancer clinical trials with a prospective control on binary endpoints (II) : Fisher's exact test -- 9. Randomized phase II trials with heterogeneous patient populations : stratified Fisher's exact test -- 10. Randomized phase II clinical trials based on survival endpoints : two-sample log-rank test -- 11. Some flexible phase II clinical trial designs.
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Includes bibliographical references and index.

1. Introduction -- 2. Single-arm phase II trial designs -- 3. Inference on the binomial probability in single-arm multistage clinical trials -- 4. Single-arm phase II clinical trials with time-to-event endpoints -- 5. Single-arm phase II trials with heterogeneous patient populations : binary and survival outcomes -- 6. Randomized phase II trials for selection : no prospective control arms -- 7. Randomized phase II cancer clinical trials with a prospective control on binary endpoints (I) : two-sample binomial test -- 8. Randomized phase II cancer clinical trials with a prospective control on binary endpoints (II) : Fisher's exact test -- 9. Randomized phase II trials with heterogeneous patient populations : stratified Fisher's exact test -- 10. Randomized phase II clinical trials based on survival endpoints : two-sample log-rank test -- 11. Some flexible phase II clinical trial designs.

Also available as an electronic resource.

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