WHO Expert Committee on Biological Standardization : thirty-seventh report, meeting held in Geneva from 1 to 8 December 1986

General -- Substances: Antibiotics -- Antibodies -- Blood products and related substances -- Endocrinological and related substances -- Miscellaneous -- requirements for biological substances -- Annaxes

Announces changes in the status or development of international standards for 35 biologicals, classified as antibiotics, antibodies, antigens, blood products and related substances, endocrinological and related substances, and a miscellaneous group of substances. The report also provides detailed information on requirements for the manufacturing, testing, and quality control of selected vaccines, including hepatitis B vaccines made by recombinant DNA techniques in yeast, live mumps vaccine, and inactivated rabies vaccine produced in continuous cell lines. Of particular practical interest is an extensive report on a WHO meeting concerned with the use of recombinant DNA techniques to produce hepatitis B vaccines. The report also includes amendments to previous requirements for oral poliomyelitis vaccine and for diphtheria toxoid, pertussis vaccine, tetanus toxoid, and combined vaccines.