Randomized phase II cancer clinical trials - Jung, Sin-Ho. (Boca Raton, Fla. : Taylor & Francis Group, 2013)
1. Introduction -- 2. Single-arm phase II trial designs -- 3. Inference on the binomial probability in single-arm multistage clinical trials -- 4. Single-arm phase II clinical trials with time-to-event endpoints -- 5. Single-arm phase II trials with heterogeneous patient populations : binary and survival outcomes -- 6. Randomized phase II trials for selection : no prospective control arms -- 7. Randomized phase II cancer clinical trials with a prospective control on binary endpoints (I) : two-sample binomial test -- 8. Randomized phase II cancer clinical trials with a prospective control on binary endpoints (II) : Fisher's exact test -- 9. Randomized phase II trials with heterogeneous patient populations : stratified Fisher's exact test -- 10. Randomized phase II clinical trials based on survival endpoints : two-sample log-rank test -- 11. Some flexible phase II clinical trial designs.
Includes bibliographical references and index.
Also available as an electronic resource.
Keywords: Clinical trials