TY - BOOK AU - MacKenzie, Gilbert. AU - Peng, Defen. TI - Statistical modelling in biostatistics and bioinformatics: selected papers T2 - Contributions to statistics SN - 9783319045788 (hard cover : alk. paper) U1 - 000SB:570 23 PY - 2014/// CY - Switzerland PB - Springer KW - Biometry. KW - Bioinformatics. KW - NATURE / Reference N1 - Introduction -- Part I. Survival Modelling Multivariate Interval-Censored Survival Data: Parametric, Semi-Parametric and Non-Parametric Models; MacKenzie and Ha -- Multivariate Survival Models Based on the GTDL; Lynch and MacKenzie -- Frailty Models with Structural Dispersion; Martinez and Hinde -- Random Effects Ordinal Time Models for Grouped Toxicological Data from a Biological Control Assay -- Part II. Longitudinal Modelling & Time Series Modelling Seasonality and Structural Breaks: Visitors to NZ and 9/11; Allais and Bosco -- Forecasting the Insolvency Risk of the Customers of an Automotive Financial Service; Xu and MacKenzie -- On Joint Modelling of Constrained Mean and Covariance Structures in Longitudinal Data -- Part III. Statistical Model Development Hierarchical Generalized Nonlinear Models; Durio and Isaia -- Comparing Robust Regression Estimators to Detect Data Clusters: A Case Study; Coffey, Hinde and Garcia -- Finite Mixture Model Clustering of SNP Data; Peng and MacKenzie -- Discrepancy and Choice of Reference Subclass in Categorical Regression Models -- Part IV. Applied Statistical Modelling Statistical Methods for Detecting Selective Sweeps; Brophy, Gibson, Wayne and Connolly -- A Mixture Model and Bootstrap Analysis to Assess Reproductive Allocation in Plants; Conde and MacKenzie -- On Model Selection Algorithms in Multi-Dimensional Contingency Tables -- Postscript: Durio and MacKenzie -- Obituary: Professor Ennio Isaia N2 - This book presents selected papers on statistical model development related mainly to the fields of Biostatistics and Bioinformatics. The coverage of the material falls squarely into the following categories: (a) Survival analysis and multivariate survival analysis, (b) Time series and longitudinal data analysis, (c) Statistical model development and (d) Applied statistical modelling. Innovations in statistical modelling are presented throughout each of the four areas, with some intriguing new ideas on hierarchical generalized non-linear models and on frailty models with structural dispersion ER -