TY  - BOOK
AU  - Mazza,Christian
AU  - Benaim,Michel
TI  - Stochastic dynamics for systems biology
T2  - Chapman & Hall/CRC Mathematical and Computational Biology Series
SN  - 9781466514935
U1  - 570.285 23
PY  - 2014///
CY  - Boca Raton
PB  - CRC Press
KW  - Systems biology
KW  - Mathematical models
KW  - Gene expressions
KW  - Statistical methods
KW  - Statistical methods.
N1  - Includes bibliographical references (p. 243-255) and index; 1. Reaction networks: introduction --
2. Continuous-time Markov chains --
3. First-order chemical reaction networks --
4. Biochemical pathways --
5. Binding processes and transcription rates --
6. Kinetics of binding processes --
7. Transcription factor binding at nucleosomal DNA --
8. Signalling switches --
9. Differential equations, flows and vector fields --
10. Equilibria, periodic orbits and limit cycles --
11. Linearisation --
12. Density dependent population processes and the linear noise approximation --
13. Mass action kinetics --
V Appendixes: 
A. Self-regulated genes --
 B. Asymptotic behaviour of the solutions to time-continuous Lyapunov equations--

Bibliography--
Index
N2  - Books to provide a systematic study of the many stochastic models used in systems biology. The book shows how the mathematical models are used as technical tools for simulating biological processes and how the models lead to conceptual insights on the functioning of the cellular processing system. Most of the text should be accessible to scientists with basic knowledge in calculus and probability theory.
ER  -