TY - BOOK AU - Looney,Stephen W. AU - Hagan,Joseph L. TI - Analysis of biomarker data: a practical guide SN - 9781118027554 U1 - 000SB:610.28 23 PY - 2015/// CY - New Jersey PB - John Wiley KW - Biochemical markers KW - statistical methods KW - Biomarkers KW - analysis KW - Statistical data interpretation N1 - Includes bibliographical references and index; 1. Introduction -- 2. Designing biomarker studies -- 3. Elementary statistical methods for analyzing biomarker data -- 4. Frequently encountered challenges in analyzing biomarker data and how to deal with them -- 5. Validation of biomarkers -- References -- Solutions to problems -- Index N2 - The authors provide descriptions of select elementary statistical methods that are traditionally used to analyze biomarker data with a focus on the proper application of each method, including necessary assumptions, software recommendations, and proper interpretation of computer output. In addition, the book discusses frequently encountered challenges in analyzing biomarker data and how to deal with them, methods for the quality assessment of biomarkers, and biomarker study designs ER -