TY  - BOOK
AU  - Burgess,Stephen
AU  - Thompson,Simon G.
TI  - Mendelian randomization: methods for using genetic variants in causal estimation 
T2  - Chapman & Hall/CRC interdisciplinary statistics series
SN  - 9781466573178
U1  - 000SB:616.042 23
PY  - 2015///
CY  - Boca Raton
PB  - CRC Press, 
KW  - Medical genetics
KW  - Statistical methods
N1  - Includes bibliographical references and index; 1. Introduction and motivation --
2. What is Mendelian randomization? --
3. Assumptions for causal inference --
4. Methods for instrumental variable analysis --
5. Examples of Mendelian randomization analysis --
6. Generalization of estimates from Mendelian randomization --
7. Weak instruments and finite-sample bias --
8. Multiple instruments and power --
9. Multiple studies and evidence synthesis --
10. Example: The CRP CHD genetics collaboration --
11. Future directions
N2  - This book gives statisticians, epidemiologists, and geneticists the foundation to understand issues concerning the use of genetic variants as instrumental variables. It will get them up to speed in undertaking and interpreting Mendelian randomization analyses
ER  -