000			02286cam a2200253 i 4500
001			136058
003			ISI Library, Kolkata
005			20150901171547.0
008			130813s2014 nju b 001 0 eng
020			_a9780691156460 (hardcover : acidfree paper)
040			_aISI Library
082	0	0	_a571.85 _223 _bW133
100	1		_aWagner, Gunter P.
245	1	0	_aHomology, genes, and evolutionary innovation / _cGunter P. Wagner.
260			_aPrinceton ; Oxford : _bPrinceton University Press, _cc2014.
300			_axiii, 478 p. : _bill. ; _c24 cm.
504			_aIncludes bibliographical references (pages 427-465) and index.
505	0		_aIntroduction. What this book aims to do and what it is not -- 1. The intellectual challenge of morphological evolution : a case for variational structuralism -- 2.A conceptual roadmap to homology -- 3. A genetic theory of homology -- 4. Evolutionary novelties : the origin of homologs -- 5. Developmental mechanisms for evolutionary novelties -- 6. The genetics of evolutionary novelties -- 7. The long shadow of metaphysics on research programs -- 8. Cell types and their origins -- 9. Skin and a few of its derivatives -- 10. Fins and limbs -- 11. Digits and digit identity -- 12. Flowers -- 13. Lessons and challenges-- References-- Index.
520			_aThis book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks - that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems.
650		0	_aDevelopmental genetics.
650		0	_aEvolution (Biology)
650		0	_aGenetic regulation.
942			_2ddc _cBK
999			_c419548 _d419548